Welcome to this week’s edition of The Guide ⚡️ 

Today’s newsletter takes about 5 minutes to read—so if you’ve only got 60 seconds, here’s what you need to know:

• New psilocybin insights. Growing research points to short-term mood shifts and lasting brain and mood changes when support and therapy are part of the process.

• Psilocybin vs. psilocybin-assisted therapy. The medicine can open a door, but the biggest gains often come from prep, safe set/setting, and guided integration, not the dose alone.

• Next steps. If you’re interested in pursuing psilocybin, check your laws, look for experienced and trained providers, and practice structured pre/post-integration practices.

• The Webdelics Podcast. Scott Mason talks with Maggie Kirkwood about how psilocybin helped her overcome her daily drinking habits to achieve sobriety and deep healing.

📺️ Don’t forget to join us for our first ever Ask Me Anything (AMA) with Steve Elfrink and Dr. Ian Luepker this evening at 5 PM PST / 7 PM CST / 8 PM EST where they will be doing a deep dive into psilocybin and it’s therapeutic uses.

👉️ Click HERE to register and join!

🧠 The Webdelics Team

👋 New here? We do this every week… Join Us!

🎧️ The Webdelics Podcast

🎙️ Psilocybin, Recovery & Grief with Maggie Kirkwood

Host Scott Mason talks with Maggie Kirkwood about the healing path she found with psilocybin. Maggie shares how magic mushrooms supported her shift from daily drinking to sobriety, and how guided experiences helped her move through profound grief, eventually opening space for meaning, connection, and self‑trust.

🫶 They explore why intention, set & setting, and integration matter, along with the stigma around mental health and psychedelics, the Midwest drinking culture, and practical first steps for anyone curious about plant medicine, including microdosing frameworks, supportive music, community, and intentional care practices.

 🧠 Why Psilocybin? Join the Live AMA Today!

🍄 We’re hosting a live, unscripted conversation with Steve Elfrink and Dr. Ian Luepker on the science, spirituality, and healing potential of psilocybin…

They’ll explore mental health, trauma, therapy, and what’s next for psychedelics in real-world practice.

🗓 Thursday, November 13th
🕔 5 PM PST / 7 PM CST / 8 PM EST
📍 Streaming on all Webdelics + Nobody Studios channels

👉 Reserve Your Spot: https://www.linkedin.com/events/7392238726543773697/ 

⁉️ Have questions?! We have answers! Ask us your questions anonymously here: https://forms.gle/3nZnp2HbqGrLDUTm8

📜 The “Must Read” For The Week

The Effects of Psilocybin Mushrooms 🍄 

Psilocybin (AKA “magic mushrooms”) is a classic psychedelic that can change how you see, feel, and think, with the effects often lasting for hours depending on the dose and set/setting…

👉️ Here’s the rundown of what we know and what to expect with psilocybin mushrooms…

💫 What To Expect (Based on Studies & Subjective Experiences in Trials)

• Colors can look brighter / Music can feel deeper / Time can feel slow or fast.

• You may “see” patterns with your eyes closed.

• Some people can even taste colors or “see” sounds (this is called synesthesia).

• New ideas may come easier / Creativity can be enhanced.

• Old memories can feel strong.

• Big feelings, good or hard.

• Support, music, and a calm place can help ease people into various states.

• You may feel more connected to people and nature.

• The “me” feeling can soften or even fade for a while (ego dissolution).

• Many rate this as very meaningful, and often, one of the most meaningful experiences of their lives.

🪜 Stages of A Psilocybin Experience

• Duration/Time - Lasts about 4–7 hours in duration; Onset is 10–60 minutes; Peaks around 90–120 minutes.

• Dose - Dosing is tricky, but a “macrodose” is considered anything between 1-5g of dried mushrooms

• The Importance of Set and Setting - Your mindset, support, and space shape the experience, and thus, the outcomes.

🔬 What the Research Supports

• Major Depressive Disorder (MDD) and Treatment-Resistant Depression

• Obsessive-Compulsive Disorder (OCD) and Related Disorders

• Addiction & Substance Use Disorders (SUD)

• Post-Traumatic Stress Disorder (PTSD)

• Neurodegenerative Disorders

• Suicide Prevention

• Cancer-Related Anxiety and Mental Distress

🦺 Safety Should Always Come First

• It’s always best to go into an experience with the right mindset, a trusted guide or clinician, and a safe setting.

• Check health history and medicines with a professional before considering psilocybin, even for spiritual endeavors.

• Laws vary by place. Follow your local rules!

👉️ Subscribe to The Guide for evidence-based takes on psychedelics, research, and integration tools—delivered weekly to your inbox.

💬 Our Why…

👉 Information only helps if it leads to wiser choices.

Psilocybin can open a door. What you do around it (prep, set/setting, support, and integration) often shapes the outcome…

If today’s issue helped you see the bigger picture, try one of these small steps:

• Go deeper: Get your FREE Beginner’s Guide to Psilocybin

• Listen in: Webdelics podcast with Maggie Kirkwood on recovery & grief

• Tune out: It’s time to dive deep and learn as much as you can!

At Webdelics, our promise is to give you clear, evidence-based guidance so you can make safer, more informed choices about psychedelics and plant medicines.

📩 If this helped, forward it to one friend who’d appreciate it…
💬 Questions, corrections, or have a topic you want us to unpack? Hit reply—we’re listening!

Stay curious. Stay kind. Keep learning.

🧠 The Guide - by Webdelics

Disclaimer: Webdelics does not support or promote any illegal activities, including the use of substances that may be mentioned in this newsletter. We encourage all readers to familiarize themselves with and adhere to the laws in their region. Please note that Webdelics does not offer mental health, medical, or clinical services and should not be used as a replacement for professional medical, psychological, or psychiatric care, diagnosis, or treatment.