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đ§ Plant Medicine and Neuroplasticity - Friend or Foe?
Plant medicines and psychedelics promote neuroplasticity, but that doesn't mean neuroplasticity is a good thing...


Explore the World of Plant Medicine and Psychedelics. A Weekly Digest of Exclusive Stories, Insights, and Research.

đ§ď¸ The Webdelics Podcast

đ Top Article
The Myth of the Rewired Brain - A Personal Journey of Healing
By Steve Elfrink at Omterra
Weâve all heard it - psychedelics rewire the brain.
They boost BDNF, stimulate synaptogenesis, reopen critical periodsâŚAnd healing just happensâor so the story goes.
But neuroplasticity is a double-edged swordâŚ
It doesnât guarantee beneficial growthâit simply creates the conditions for change. What actually gets wired depends entirely on the terrain underneath.
And for many of us, that terrain is trauma.
đ Neuroplasticity â Healing
Psychedelics can increase brain flexibilityâbut if your nervous system is dysregulated or stuck in trauma loops, more plasticity can mean more chaos.
đ§ââď¸ Trauma Is Stored in the Body
Porgesâ Polyvagal Theory explains why trauma isnât just mentalâitâs physiological. Locked in patterns of fight, flight, or freeze, our bodies replay ancient survival responses that psychedelics alone canât undo.
â ď¸ The Risk of Psychedelic Iatrogenesis
When the Default Mode Network collapses under high-dose psychedelics, unprocessed trauma may flood the system. For trauma survivors, this can feel less like liberationâand more like fragmentation.
đ§ââď¸ The Real Work - Somatic Integration
For me, healing began when I stopped chasing transcendence and started listening to my body. Through PSIT (Psycholytic Somatic Integration Therapy), I engaged with the parts that never got to finish their survival responses.
đŚ Sometimes, You Need To Change The Course of Healing To Change Your Healing
âPsychedelics can unlock doorsâbut they donât rebuild the house.â
True healing requires more than molecules. It takes relational safety, body-based integration, and the courage to reconnect with the parts of ourselves psychedelics may expose but cannot resolve.
If youâve done the work and still feel broken, youâre not brokenâŚ
Youâre healingâand maybe, itâs time to come home to your body.
đ Research/References
Ly et al. (2018), Cell Reports â Psychedelics and neural plasticity
Porges (2011), The Polyvagal Theory â Foundations of trauma physiology
Carhart-Harris et al. (2014), Frontiers in Human Neuroscience â The Entropic Brain
Elfrink & Bergin (2024), Frontiers in Psychology â Psychedelic Iatrogenic Structural Dissociation (PISD)

đ Top Weekly Blog!
Our Top Psychedelic and Plant Medicine Blog from Webdelics
The Webdelics website has over 160+ evidence-based, research-backed blogs that were intentionally written to give you the facts, not just our opinions.
đď¸ Here is this weekâs top blog on our site, rated by our readers:
đ How much is too much-or not enough?
This reader-favorite guide demystifies the art and science of psilocybin dosing, from microdoses to macrodoses and everything in between.
đ Youâll get clear breakdowns of how different dosages affect perception, duration, and therapeutic potentialâplus expert-backed tips on how to find your ideal range.
đĄ New to mushrooms? Nervous about âtoo far, too fastâ? Start here!

đŹ We will leave you with thisâŚ
We live in a culture obsessed with quick fixesâreset buttons, miracle molecules, magic mushrooms. But real healing rarely moves at the speed of hype.
It moves at the speed of trust.
Of breath.
Of slowly, safely returning to the body we left behind.
đ§ Psychedelics can be powerful allies. But theyâre not the path. You are.
And if youâve walked that path only to find yourself back in the same pain, know this:
Youâre not doing it wrong.
Youâre not broken.
Youâre at the beginning of something deeper.
đĄ Sometimes, the most radical thing we can do is pause, turn inward, and finally listen to whatâs been there all alongâwaiting to be felt, not fixed.
Weâll be here when you do.
Until next timeâŚ
đ§ The Guide - by Webdelics
Disclaimer: Webdelics does not support or promote any illegal activities, including the use of substances that may be mentioned in this newsletter. We encourage all readers to familiarize themselves with and adhere to the laws in their region. Please note that Webdelics does not offer mental health, medical, or clinical services and should not be used as a replacement for professional medical, psychological, or psychiatric care, diagnosis, or treatment.

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