Honoring the Visionaries - Webdelics’ Top 100 Psychedelic Thought Leaders and Content Creators 🌟 

The wait is over!

We’re proud of this one and the feedback has been monumental!

Last week we published the Top 100 Psychedelic Thought Leaders and Content Creators a celebration of the innovators pushing boundaries in psychedelics, mental health, and alternative therapies.

🔗 Check out the full list here:

https://www.webdelics.com/top-lists/thought-leaders-content-creators

At Webdelics, our mission is to educate, inspire, and build a community around the transformative potential of psychedelics…

By highlighting these leaders, we’re taking one step closer to reshaping the narrative and creating a brighter future for mental health and human potential.

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 Let’s celebrate the trailblazers leading the way! 🌱

🧠 The Webdelics Team

📔 Psychedelics 101: Terms Everyone Should Know

Ego Dissolution ☁️

Who are you… when the “you” disappears?

👁️ Ego dissolution refers to the temporary loss of your sense of self—an experience common in high-dose psychedelic journeys.

It’s the unraveling of identity, where the boundaries between “self” and “other” blur or vanish altogether. For some, it’s terrifying. For others, liberating.

Why does this matter?

🧬 Many describe ego death as the most profound part of their journey—where fear, control, and separateness dissolve, making room for awe, unity, or deep surrender. In therapeutic settings, this collapse of the ego can be a gateway to healing trauma and reimagining who you are beyond your past.

🎧️ The Webdelics Podcast

📜 Top Article

🧬 From Lab Bench to Dance Floor - The Underground History of MDMA

MDMA, known today as “ecstasy” or “Molly,” has a complex and fascinating history that spans over a century…

First synthesized in 1912 by German chemist Anton Köllisch at Merck Pharmaceuticals, MDMA was initially developed as a precursor in the creation of a substance intended to stop bleeding.

Despite its early synthesis, the psychoactive properties of MDMA remained largely unexplored for decades.​

🌱 The Rise of MDA and the Path to MDMA

Before MDMA gained prominence, its chemical cousin MDA (3,4-methylenedioxyamphetamine) was the subject of medical research in the 1950s and 1960s.

Although pharmaceutical companies tested MDA for various medical indications, the pursuit was abandoned due to unwanted central side effects.

Nevertheless, MDA found its way into the recreational scene in the mid-1960s, earning the nickname “The Love Drug” for its euphoric and sense-enhancing effects.

The scheduling of MDA under the Controlled Substances Act in 1970 curtailed its legal availability, but underground chemists continued to produce and distribute it, keeping its presence alive in both recreational and therapeutic contexts.

🔬 MDMA's Emergence and Underground Popularity

In 1960, Polish chemists Stanislaw Biniecki and Edmund Krajewski published a report detailing the synthesis of MDMA from safrole, marking a significant point in its history.

However, it wasn't until the 1970s that MDMA began to gain attention for its psychoactive properties.​..

American chemist Alexander “Sasha” Shulgin synthesized MDMA in 1965, but it wasn't until the mid-1970s that he explored its psychoactive effects.

Impressed by its potential, Shulgin introduced MDMA to psychotherapist Leo Zeff, who recognized its value in therapy.

Zeff trained hundreds of therapists in the use of MDMA, which he called “Adam,” believing it helped patients achieve a state of primordial innocence.​

🚫 Legal Challenges and Cultural Impact

As MDMA's popularity grew, so did concerns about its unregulated use.

In 1985, the U.S. Drug Enforcement Administration (DEA) classified MDMA as a Schedule I controlled substance, citing its potential for abuse and lack of accepted medical use.

This move significantly impacted both recreational and therapeutic use, pushing MDMA further into the underground scene…

Despite legal challenges, MDMA's influence continued to spread, particularly within the rave and electronic dance music cultures of the late 1980s and 1990s.

Its reputation as a party drug often overshadowed its therapeutic origins, but interest in its potential benefits never fully disappeared.​

🧠 Renewed Interest and Ongoing Research

In recent years, there has been a resurgence of interest in MDMA's therapeutic potential, particularly in the treatment of post-traumatic stress disorder (PTSD).

Clinical trials have shown promising results, leading to discussions about the possibility of MDMA-assisted therapy becoming an approved treatment option in the near future.​

⁉️ Where do you think the future of MDMA lies?

We would love to hear from you!

🎉 Top Weekly Blog!

Our Top Psychedelic and Plant Medicine Blog from Webdelics

The Webdelics website has over 160+ evidence-based, research-backed blogs that were intentionally written to give you the facts, not just our opinions. 

📚️ Here is this week’s top blog on our site, rated by our readers:

• Ibogaine and Traumatic Brain Injury - Pioneering a Psychedelic Path to Recovery

This one challenges a lot of what we think we know about psychedelics and plant medicines…

👉️ Check it out and let us know what you think!

💬 We will leave you with this…

Tim Hunt was quoted saying, “Science is about nothing but getting at the truth, and anything that gets in the way of that diminishes, in my experience, the science.”

Life has an interesting way of teaching us things we need to know and things we didn’t realize we needed to know.

Until next time…

🧠 The Guide - by Webdelics

Disclaimer: Webdelics does not support or promote any illegal activities, including the use of substances that may be mentioned in this newsletter. We encourage all readers to familiarize themselves with and adhere to the laws in their region. Please note that Webdelics does not offer mental health, medical, or clinical services and should not be used as a replacement for professional medical, psychological, or psychiatric care, diagnosis, or treatment.